Osteosarcoma (OS) is a malignant type of bone cancer that arises in periods of increased bone formation.Curative strategies for these types of tumors have remained essentially unchanged for decades and the overall survival for most advanced cases is still dismally low.This is in part due to the existence of drug resistant Cancer Stem Cells (CSC) wi
Two-dipole model of the asymmetric Sun
The large-scale photospheric magnetic field is commonly thought to be mainly dipolar during sunspot minima, when magnetic fields of opposite polarity cover the solar poles.However, recent studies show that the octupole harmonics contribute comparably to the spatial power of the photospheric field at these times.Also, the even harmonics are non-zero
A multi-level implementation strategy to increase adoption of chiropractic care for low back pain in primary care clinics: a randomized stepped-wedge pilot study protocol
Abstract Introduction Limited adoption of first line treatments for low back pain (LBP) in primary care settings may contribute to an overreliance on pain medications by primary care providers (PCPs).While chiropractic care typically includes recommended nonpharmacologic approaches (e.g., manual therapy, exercise instruction, advice on self-care),
From soil to plant: strengthening carrot defenses against Meloidogyne incognita with vermicompost and arbuscular mycorrhizal fungi biofertilizers
IntroductionSustainable agricultural practices for controlling crop pests are urgently needed to reduce the reliance on chemical pesticides, which have long-term detrimental effects on ecosystems.In this study, we assessed the effectiveness of arbuscular mycorrhizal fungi (AMF) and vermicompost (Vc) supplementation, alone and in combination, in mit
Fundamentals of the historical development of theater acting from Ancient Greece and Rome to the modern and avant-garde
The research subject of this paper is oriented on the development of acting through the focus of the actor as an artist and acting itself as an art.Answers are given in the paper, who were all the actors and what acting tools they used.Furthermore, in which period dramatic theater prevailed, theater based on elements of drama, and when was it creat